Project Description

Shu Meng obtained her MD and MS in Medical Genetics from Sun Yat-sen University School of Medicine in China. She then earned her PhD in Pharmacology from the Pharmacology Department and Cardiovascular Research Center of Temple University School of Medicine under the supervision of Dr. Hong Wang. During her PhD studies, she demonstrated that hyperhomocysteinemia, a cardiovascular risk factor, accelerates thrombosis though ICAM-1 dependent endothelial activation though DNA hypomethylation mechanism. Shu Meng joined Dr. Cooke’s lab as a postdoctoral fellow in 2013 to work on the transdifferentiation of fibroblasts into functional endothelial cells using chemical entity based methods. She is particularly interested in using small molecules as a therapeutic approach to reprogram and generate healthy endothelial cells in vivo. She is also involved in characterizing several transcription factors and their role in endothelial development. In her spare time, Shu enjoys to listen to music, travel and spend time with her family.